Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | SMYD2 | Q9NRG4 | 8/20 | 0.58 |
| ▸ | HTR2A | P28223 | 4/20 | 0.55 |
| ▸ | HTR2C | P28335 | 4/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28598516 | 0.92 | NPSR1 (0.56) | KMT2AMEN1SMYD2HTR2AHTR2C | |
| SCHEMBL13164073 | 0.88 | SMYD2 (0.62) | SMYD2 | |
| SCHEMBL28598737 | 0.88 | MEN1 (0.57) | KMT2AMEN1SMYD2HTR2AHTR2C | |
| SCHEMBL13164069 | 0.84 | HPGD (0.59) | SMYD2 | |
| SCHEMBL28612189 | 0.84 | TSHR (0.58) | — | |
| SCHEMBL14430681 | 0.83 | ALDH1A1 (0.57) | KMT2AMEN1 | |
| SCHEMBL13164063 | 0.81 | NPSR1 (0.58) | KMT2AMEN1 | |
| SCHEMBL14430692 | 0.80 | KMT2A (0.61) | KMT2AMEN1SMYD2HTR2AHTR2C | |
| SCHEMBL13164061 | 0.80 | NPSR1 (0.59) | KMT2AMEN1 | |
| SCHEMBL9064849 | 0.80 | HTR4 (0.55) | KMT2AMEN1SMYD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113195497-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | claimed |
| CN-113195497-A | Novel imidazopyrazine derivatives | 豪夫迈·罗氏有限公司 | 2021-07-30 | — | — | CN | disclosed |