Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.45 |
| ▸ | CPT1A | P50416 | 3/20 | 0.45 |
| ▸ | CPT1B | Q92523 | 2/20 | 0.44 |
| ▸ | CPT2 | P23786 | 1/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.42 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28920514 | 0.94 | HTR6 (0.45) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL28920494 | 0.91 | MAPT (0.52) | HTR6 | |
| SCHEMBL28920367 | 0.90 | HTR6 (0.45) | HTR6HTR1A | |
| SCHEMBL28920446 | 0.90 | HTR6 (0.45) | HTR6HTR7 | |
| SCHEMBL28920387 | 0.90 | STS (0.45) | HTR6CPT1ACPT1BCPT2CYP2C9 | |
| SCHEMBL30091124 | 0.86 | HTR6 (0.47) | HTR6CPT1ACPT1BCPT2HTR3E | |
| SCHEMBL28920456 | 0.86 | HTR6 (0.55) | HTR6CPT1AHTR3EHTR3BHTR3A | |
| SCHEMBL30091180 | 0.86 | HTR6 (0.60) | HTR6HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL30091257 | 0.86 | HTR6 (0.55) | HTR6CPT1AHTR3EHTR3BHTR3A | |
| SCHEMBL28920489 | 0.86 | HTR6 (0.60) | HTR6HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232362-B | Aromatic heterocyclic derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |