Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10044915 | 0.82 | HSP90AB1 (0.69) | CYP19A1SIGMAR1HSP90AB1HRH4NPC1 | |
| SCHEMBL936304 | 0.79 | CYP19A1 (0.57) | CYP19A1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL12205813 | 0.79 | CYP19A1 (0.65) | CYP19A1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL15014123 | 0.77 | CYP19A1 (0.76) | CYP19A1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL18160688 | 0.76 | CYP19A1 (0.61) | CYP19A1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL13070779 | 0.76 | CYP19A1 (0.61) | CYP19A1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL230368 | 0.75 | HSP90AB1 (0.82) | CYP19A1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL30959784 | 0.74 | HSP90AB1 (0.80) | CYP19A1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL2641384 | 0.74 | CYP19A1 (1.00) | CYP19A1HSP90AB1HRH4NPC1RAB9A | |
| SCHEMBL21293881 | 0.74 | HSP90AB1 (0.80) | CYP19A1HSP90AB1HRH4NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294725-B | Derivative of sponge furanone and catalytic synthesis method thereof | 广东医科大学 | 2022-08-09 | — | — | CN | disclosed |
| CN-113214162-A | Preparation method of benzimidazole derivative | 南方海洋科学与工程广东省实验室(湛江) | 2021-08-06 | — | — | CN | disclosed |