Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.50 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | HPD | P32754 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29110467 | 0.88 | KMT2A (0.60) | KMT2AKCNH2HRH3NPC1POLB | |
| SCHEMBL28924717 | 0.86 | POLB (0.59) | KMT2AKCNH2HRH3POLBHDAC3 | |
| SCHEMBL28961933 | 0.84 | POLB (0.60) | KCNH2HRH3POLBHDAC3APP | |
| SCHEMBL29103865 | 0.80 | MAPK1 (0.70) | KCNH2HRH3POLBMAPK1 | |
| SCHEMBL29110441 | 0.79 | HSD17B10 (0.72) | KMT2AKCNH2HRH3POLBGRM1 | |
| SCHEMBL28924733 | 0.78 | POLB (0.75) | KCNH2HRH3NPC1POLBHDAC1 | |
| SCHEMBL30149510 | 0.77 | NPC1 (0.46) | KCNH2HRH3NPC1POLBGRM1 | |
| SCHEMBL28924735 | 0.77 | NPC1 (0.46) | KCNH2HRH3NPC1POLBGRM1 | |
| SCHEMBL4391482 | 0.77 | MAPK1 (0.70) | KMT2ANPC1POLBGRM1CYP1A2 | |
| SCHEMBL31463104 | 0.77 | NPC1 (0.71) | KCNH2HRH3NPC1POLBGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521261-B | Preparation method of mercapto-containing quinazolinone and composition thereof, and application of mercapto-containing quinazolinone in resisting kiwi fruit canker | 贵州理工学院 | 2024-04-05 | — | — | CN | disclosed |
| CN-115521261-A | Preparation method of sulfhydryl-containing quinazolinone and composition thereof and application of sulfhydryl-containing quinazolinone in resisting kiwifruit canker | 贵州理工学院 | 2022-12-27 | — | — | CN | disclosed |