Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28924646 | 0.89 | POLB (0.71) | POLBHRH3KCNH2L3MBTL1GLA | |
| SCHEMBL30149472 | 0.89 | POLB (0.71) | POLBHRH3KCNH2L3MBTL1GLA | |
| SCHEMBL29110476 | 0.88 | POLB (0.61) | POLBHRH3KCNH2L3MBTL1GLA | |
| SCHEMBL28924717 | 0.86 | POLB (0.59) | POLBHRH3KCNH2HDAC3APP | |
| SCHEMBL28924732 | 0.84 | KMT2A (0.58) | POLBHRH3KCNH2HDAC3APP | |
| SCHEMBL29103865 | 0.80 | MAPK1 (0.70) | POLBHRH3KCNH2L3MBTL1MAPK1 | |
| SCHEMBL29110401 | 0.79 | HSD17B10 (0.72) | POLBHRH3KCNH2L3MBTL1GLA | |
| SCHEMBL28924692 | 0.78 | POLB (0.50) | POLBHRH3KCNH2L3MBTL1GLA | |
| SCHEMBL30149515 | 0.78 | POLB (0.50) | POLBHRH3KCNH2L3MBTL1GLA | |
| SCHEMBL28924733 | 0.78 | POLB (0.75) | POLBHRH3KCNH2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115521261-B | Preparation method of mercapto-containing quinazolinone and composition thereof, and application of mercapto-containing quinazolinone in resisting kiwi fruit canker | 贵州理工学院 | 2024-04-05 | — | — | CN | disclosed |
| CN-115521261-A | Preparation method of sulfhydryl-containing quinazolinone and composition thereof and application of sulfhydryl-containing quinazolinone in resisting kiwifruit canker | 贵州理工学院 | 2022-12-27 | — | — | CN | disclosed |