Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Tetramethylammonium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetramethylammonium Ion SCHEMBL6262633 | 0.93 | — | — | |
| Tetramethylammonium Ion SCHEMBL28374142 | 0.93 | CHRNB2 (0.57) | — | |
| Tetramethylammonium Ion SCHEMBL28419141 | 0.93 | — | — | |
| Tetramethylammonium Ion SCHEMBL99504 | 0.91 | — | — | |
| Tetramethylammonium Ion SCHEMBL130472 | 0.91 | CHRNB2 (0.80) | — | |
| Tetramethylammonium Ion SCHEMBL1520826 | 0.91 | — | — | |
| Tetramethylammonium Ion SCHEMBL22436611 | 0.91 | CHRNB2 (0.80) | — | |
| Tetramethylammonium Ion SCHEMBL31488139 | 0.91 | CHRNB2 (0.80) | — | |
| Tetramethylammonium Ion SCHEMBL9170680 | 0.83 | CHRNB2 (0.67) | — | |
| Tetramethylammonium Ion SCHEMBL11873207 | 0.83 | CHRNB2 (0.67) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7655129-B2 | Binding acceleration techniques for the detection of analytes | OSMETECH TECHNOLOGY INC. (US) | 2010-02-02 | — | — | US | disclosed |
| US-20080108074-A1 | Methods and Compositions for Efficient Nucleic Acid Sequencing | DRMANAC RADOJE T | 2008-05-08 | — | — | US | disclosed |
| US-20080050393-A1 | Novel nucleic acids and polypeptides | NUVELO, INC. (A NEVADA CORPORATION) | 2008-02-28 | — | — | US | disclosed |
| US-7087148-B1 | Binding acceleration techniques for the detection of analytes | CLINICAL MICRO SENSORS, INC. (US) | 2006-08-08 | — | — | US | disclosed |
| US-7070927-B2 | Methods and compositions for efficient nucleic acid sequencing | UNIVERSITY OF CHICAGO (US) | 2006-07-04 | — | — | US | disclosed |
| US-7001731-B2 | Chemokine receptor obtained from a cDNA library of fetal liver-spleen | NUVELO, INC. (US) | 2006-02-21 | — | — | US | disclosed |
| US-6979548-B2 | Chemokine receptor obtained from a CDNA library of fetal liver-spleen | NUVELO, INC. (US) | 2005-12-27 | — | — | US | disclosed |
| US-20050244954-A1 | Binding acceleration techniques for the detection of analytes | OSMETECH TECHNOLOGY INC. | 2005-11-03 | — | — | US | disclosed |
| US-20050222393-A1 | Antibody specific for a chemokine receptor; immunoassay and kits | HYSEQ, INC. | 2005-10-06 | — | — | US | disclosed |
| US-20050003399-A1 | Binding acceleration techniques for the detection of analytes | CLINICAL MICRO SENSORS, INC., (DBA OSMETECH TECHNOLOGY INC.) | 2005-01-06 | — | — | US | disclosed |
| EP-1012335-A1 | METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES | HYSEQ, INC. (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-2000000515-A2 | A CHEMOKINE RECEPTOR OBTAINED FROM A cDNA LIBRARY OF FETAL LIVER-SPLEEN | HYSEQ, INC. (US) | 2000-01-06 | — | — | WO | disclosed |
| EP-0968305-A1 | METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES | HYSEQ, INC. (US) | 2000-01-05 | — | — | EP | disclosed |
| WO-1999067425-A2 | BINDING ACCELERATION TECHNIQUES FOR THE DETECTION OF ANALYTES | CLINICAL MICRO SENSORS, INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| WO-1999041382-A2 | A NOVEL INTERLEUKIN-3 AND USES THEREOF | HYSEQ, INC. (US) | 1999-08-19 | — | — | WO | disclosed |
| WO-1999036567-A2 | ENHANCED DISCRIMINATION OF PERFECT MATCHES FROM MISMATCHES USING A MODIFIED DNA LIGASE | HYSEQ, INC. (US) | 1999-07-22 | — | — | WO | disclosed |
| WO-1999009217-A1 | METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES | HYSEQ, INC. (US) | 1999-02-25 | — | — | WO | disclosed |
| WO-1998031836-A1 | METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES | HYSEQ, INC. (US) | 1998-07-23 | — | — | WO | disclosed |
| EP-0723598-A1 | METHODS AND COMPOSITIONS FOR EFFICIENT NUCLEIC ACID SEQUENCING | ARCH DEVELOPMENT CORPORATION (US) | 1996-07-31 | — | — | EP | disclosed |
| WO-1995009248-A1 | METHODS AND COMPOSITIONS FOR EFFICIENT NUCLEIC ACID SEQUENCING | ARCH DEVELOPMENT CORP. (US) | 1995-04-06 | — | — | WO | disclosed |