Theanine

Theanine

SCHEMBL289255

CCNC(=O)CC[C@H](N)C(=O)O.CCNC(=O)CC[C@H](N)C(=O)O

nearest known ligand 0.72

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 7/20 0.54
GRM8 O00222 1/20 0.54
GRM6 O15303 1/20 0.54
GRIN2D O15399 1/20 0.54
GRIN3B O60391 1/20 0.54
GSR P00390 1/20 0.54
CYP1A2 P05177 1/20 0.54
GRIK1 P39086 1/20 0.54
GRM5 P41594 1/20 0.54
GRIA1 P42261 1/20 0.54
GRIA2 P42262 1/20 0.54
GRIA3 P42263 1/20 0.54
SLC1A3 P43003 1/20 0.54
SLC1A2 P43004 1/20 0.54
SLC1A1 P43005 1/20 0.54
GRIA4 P48058 1/20 0.54
GRIN1 Q05586 1/20 0.54
GRIN2A Q12879 1/20 0.54
GRIK2 Q13002 1/20 0.54
GRIK3 Q13003 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Theanine SCHEMBL23581676 1.00 NOD1 (0.54) NOD1GRM8GRM6GRIN2DGRIN3B
Theanine SCHEMBL190716 1.00 NOD1 (0.54) NOD1GRM8GRM6GRIN2DGRIN3B
Theanine SCHEMBL290430 1.00 NOD1 (0.54) NOD1GRM8GRM6GRIN2DGRIN3B
Theanine SCHEMBL4906383 1.00 NOD1 (0.54) NOD1GRM8GRM6GRIN2DGRIN3B
Theanine SCHEMBL31465412 1.00 NOD1 (0.54) NOD1GRM8GRM6GRIN2DGRIN3B
Theanine SCHEMBL30738878 0.98 NOD1 (0.53) NOD1GRM8GRM6GRIN2DGRIN3B
Theanine SCHEMBL30772429 0.98 NOD1 (0.53) NOD1GRM8GRM6GRIN2DGRIN3B
Theanine SCHEMBL32665663 0.98 NOD1 (0.53) NOD1GRM8GRM6GRIN2DGRIN3B
Theanine SCHEMBL29169645 0.98 NOD1 (0.53) NOD1GRM8GRM6GRIN2DGRIN3B
Theanine SCHEMBL31112055 0.98 NOD1 (0.53) NOD1GRM8GRM6GRIN2DGRIN3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011123061-A1 AMPHIPHILIC LINEAR PEPTIDE/PEPTOID AND HYDROGEL COMPRISING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-10-06 WO claimed
US-9925307-B2 Crosslinked peptide hydrogels AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-03-27 US disclosed
US-20170182217-A1 Crosslinked Peptide Hydrogels AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-06-29 US disclosed
US-9555163-B2 2017-01-31 US disclosed
US-20150273114-A1 CROSSLINKED PEPTIDE HYDROGELS AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2015-10-01 US disclosed
US-8541184-B2 Screening for neurotoxic amino acid associated with neurological disorders THE INSTITUTE FOR ETHNOMEDICINE (US) 2013-09-24 US disclosed
EP-2427196-A1 INTRAVENOUS FORMULATION WITH WATER-SOLUBLE COCRYSTALS OF ACETYLSALICYLIC ACID AND THEANINE Soluprin Pharmaceuticals, Inc. (US) 2012-03-14 EP disclosed
WO-2011123061-A1 AMPHIPHILIC LINEAR PEPTIDE/PEPTOID AND HYDROGEL COMPRISING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2011-10-06 WO disclosed
EP-1860441-B1 Neurotoxic amino acid or neurotoxic derivative thereof associated with neurological disorders INST ETHNOMEDICINE (US) 2011-08-10 EP disclosed
US-20110183424-A1 SCREENING FOR NEUROTOXIC AMINO ACID ASSOCIATED WITH NEUROLOGICAL DISORDERS THE INSTITUTE FOR ETHNOMEDICINE (US) 2011-07-28 US disclosed
US-7901895-B2 Screening environmental samples such as food, water for beta-N-methylamino-L-alanine (BMAA) associated with risk of nervous system disorders such as dementia, amyotrophic lateral sclerosis THE INSTITUTE FOR ETHNOMEDICINE (US) 2011-03-08 US disclosed
US-7256002-B2 Screening for neurotoxic amino acid associated with neurological disorders THE INSTITUTE FOR ETHNOMEDICINE (US) 2007-08-14 US disclosed
US-20050042686-A1 Neurotoxic amino acid or neurotoxic derivative thereof associated with neurological disorders NATIONAL TROPICAL BOTANICAL GARDEN 2005-02-24 US disclosed