Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.71 |
| ▸ | BMP1 | P13497 | 1/20 | 0.62 |
| ▸ | TACR1 | P25103 | 2/20 | 0.61 |
| ▸ | ACE | P12821 | 1/20 | 0.59 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.59 |
| ▸ | CTSL | P07711 | 2/20 | 0.58 |
| ▸ | CTSS | P25774 | 1/20 | 0.58 |
| ▸ | CTSK | P43235 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | CCKBR | P32239 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29972836 | 1.00 | KMT2A (0.71) | KMT2AMEN1HCRTR1BMP1TACR1 | |
| SCHEMBL29419166 | 0.89 | TACR1 (0.65) | KMT2AMEN1HCRTR1TACR1ACE | |
| SCHEMBL7618821 | 0.88 | ACE (0.68) | KMT2AMEN1HCRTR1BMP1TACR1 | |
| SCHEMBL27332474 | 0.86 | TACR1 (0.61) | KMT2AMEN1HCRTR1TACR1ACE | |
| SCHEMBL30841400 | 0.86 | TACR1 (0.61) | KMT2AMEN1HCRTR1TACR1ACE | |
| SCHEMBL621684 | 0.86 | TACR1 (0.78) | KMT2AMEN1HCRTR1TACR1ACE | |
| SCHEMBL1486155 | 0.86 | TACR1 (0.78) | KMT2AMEN1HCRTR1TACR1ACE | |
| SCHEMBL5251038 | 0.86 | TACR1 (0.78) | KMT2AMEN1HCRTR1TACR1ACE | |
| SCHEMBL29400174 | 0.86 | TACR1 (0.78) | KMT2AMEN1HCRTR1TACR1ACE | |
| SCHEMBL13702222 | 0.86 | TACR1 (0.62) | TACR1CTSLCTSSCTSKMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385846-A | Indole compound, preparation method and application thereof | 复旦大学 | 2022-11-25 | — | — | CN | disclosed |