SCHEMBL28926537

SCHEMBL28926537

O=C(CC(=O)C(F)(F)F)c1cccs1.O=C(CC(=O)C(F)(F)F)c1cccs1.O=C(CC(=O)C(F)(F)F)c1cccs1.[Eu].c1cnc2c(c1)ccc1ncccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
KDM4E B2RXH2 4/20 0.42
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
NPSR1 Q6W5P4 2/20 0.42
ALOX15 P16050 1/20 0.42
ALDH1A1 P00352 6/20 0.41
MAPT P10636 5/20 0.41
GAA P10253 2/20 0.41
HTT P42858 3/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
HSP90AA1 P07900 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ATM Q13315 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27857016 1.00 LMNA (0.48) LMNAKDM4EMEN1KMT2ANPSR1
Phenanthroline SCHEMBL6888855 0.90 MEN1 (0.47) LMNAKDM4EMEN1KMT2ANPSR1
Phenanthroline SCHEMBL3137741 0.90 MEN1 (0.47) LMNAKDM4EMEN1KMT2ANPSR1
Phenanthroline SCHEMBL3137857 0.89 KDM4E (0.48) LMNAKDM4EMEN1KMT2ANPSR1
SCHEMBL28318311 0.81 LMNA (0.56) LMNAKDM4EMEN1KMT2AALOX15
SCHEMBL27760339 0.80 LMNA (0.57) LMNAKDM4EMEN1KMT2AALOX15
SCHEMBL28396408 0.80 LMNA (0.57) LMNAKDM4EMEN1KMT2AALOX15
SCHEMBL28233757 0.79 LMNA (0.56) LMNAKDM4EMEN1KMT2AALOX15
SCHEMBL1681119 0.78 ERCC5 (0.57) LMNAKDM4EMEN1KMT2AALDH1A1
SCHEMBL3800916 0.78 ERCC5 (0.57) LMNAKDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115548240-A Gradient doped white organic electroluminescent device and preparation method thereof 中国科学院长春应用化学研究所 2022-12-30 CN claimed