Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.59 |
| ▸ | CES1 | P23141 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.37 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.37 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28055073 | 0.96 | CES2 (0.56) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL993393 | 0.96 | CES2 (0.65) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL27512061 | 0.96 | CES2 (0.56) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6937404 | 0.96 | CES2 (0.65) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL6141408 | 0.96 | CES2 (0.56) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL346017 | 0.96 | CES2 (0.65) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL31486636 | 0.96 | CES2 (0.65) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL28141435 | 0.96 | CES2 (0.65) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL27502916 | 0.96 | CES2 (0.65) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL9861947 | 0.96 | CES2 (0.65) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 169 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775535-A | Pure cation system photosensitive resin composition and preparation method thereof | 上海信斯帝克新材料有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-115135648-A | Dihydronaphthyridinone compounds, preparation method and medical application thereof | 劲方医药科技(上海)有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-111635999-A | Method for extracting lithium from lithium-containing brine and preparing lithium hydroxide | 孟元 | 2020-09-08 | — | — | CN | claimed |
| CN-111410216-A | Method for extracting lithium from water with high magnesium-lithium ratio and preparing lithium carbonate | 孟元 | 2020-07-14 | — | — | CN | claimed |
| CN-101087757-A | Novel dipeptidyl peptidase iv inhibitors, process for their preparation and compositions containing them | GLENMARK PHARMACEUTICALS SA (CH) | 2007-12-12 | — | — | CN | claimed |
| US-6677379-B2 | SUCH AS 3-((3-(3-TRIFLUOROMETHOXYPHENOXY)PHENYL)((3-(1,1,2,2-TETRAFLUOROETHOXY) -PHENYL)METHYL) AMINO)-1,1,1-TRIFLUORO-2-PROPANOL FOR TREATMENT OF CORONARY ARTERY DISEASE | PHARMACIA CORPORATION | 2004-01-13 | — | — | US | claimed |
| US-20010018446-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | G.D. SEARLE & CO. (US) | 2001-08-30 | — | — | US | claimed |
| WO-2001039766-A2 | SCREENING INVERTEBRATE PHEROMONES FOR THERAPEUTIC ACTIVITY | ALYDAR PHARMACEUTICALS LTD. (IL) | 2001-06-07 | — | — | WO | claimed |
| EP-0879219-B1 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | ABBOTT LAB (US) | 2000-03-01 | — | — | EP | claimed |
| EP-0879219-A1 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | Abbott Laboratories (US) | 1998-11-25 | — | — | EP | claimed |
| WO-1998011036-A9 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | — | 1998-07-09 | — | — | WO | claimed |
| WO-1998011036-A1 | ATTACHED TAGS FOR USE IN COMBINATORIAL CHEMISTRY SYNTHESIS | ABBOTT LABORATORIES (US) | 1998-03-19 | — | — | WO | claimed |
| CN-119775535-A | Pure cation system photosensitive resin composition and preparation method thereof | 上海信斯帝克新材料有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-118146078-A | Refining method of cyclopentyl formaldehyde | 常州沃腾化工科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-116283810-B | Preparation method of isoxazole compound | 上海麦克林生化科技股份有限公司 | 2024-04-19 | — | — | CN | disclosed |
| EP-4282973-A2 | PROCESSES FOR THE PREPARATION OF PYRIMIDINYLCYCLOPENTANE COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2023-11-29 | — | — | EP | disclosed |
| US-4097521-A | Manufacture of amidosulfonic acids | BASF AKTIENGESELLSCHAFT (DT) | 1978-06-27 | — | — | US | disclosed |
| US-4053526-A | PROCESS FOR ISOLATING DINITRONAPHTHALENES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-11 | — | — | US | disclosed |
| US-4042587-A | PESTICIDES | BASF AKTIENGESELLSCHAFT (DT) | 1977-08-16 | — | — | US | disclosed |
| US-3956316-A | PROGESTATIONAL AND SALT-RETAINING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1976-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010018446-A1 | Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity | CETP, DBI, MTTP | CES2 287/4885CES1 32/4885HDAC8 3254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.