Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 16/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.45 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 9/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 9/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 9/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
| ▸ | NAMPT | P43490 | 2/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28927109 | 0.99 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1HSP90B1HDAC3HDAC6 | |
| SCHEMBL29168557 | 0.86 | DRD2 (0.33) | NAMPTADRA1DADRA1AADRA1B | |
| Ammonia Solution, Strong SCHEMBL28927054 | 0.86 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1HSP90B1HDAC3HDAC6 | |
| SCHEMBL28927103 | 0.85 | HSP90AA1 (0.45) | HSP90AA1HSP90AB1HSP90B1HDAC3HDAC6 | |
| Ammonia Solution, Strong SCHEMBL30091877 | 0.73 | HRH3 (0.55) | HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL23673776 | 0.73 | HRH3 (0.56) | HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL30091905 | 0.73 | HRH3 (0.56) | HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL30091902 | 0.72 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL23673758 | 0.72 | HSP90AA1 (0.50) | HSP90AA1HSP90AB1HSP90B1 | |
| SCHEMBL23686707 | 0.72 | HRH3 (0.50) | HSP90AA1HSP90AB1HSP90B1HDAC3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397811-A | Isoindoline derivatives that bind to ATP binding sites | 奈奥芬莱有限公司 | 2022-11-25 | — | — | CN | disclosed |