Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23292500 | 0.87 | HPGD (0.54) | KDM4EHTTSMN1; SMN2MAPTGAA | |
| SCHEMBL5503225 | 0.86 | PPARG (0.51) | KDM4EHTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL8134302 | 0.86 | HTT (0.54) | KDM4EHTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL4241664 | 0.85 | CA12 (0.51) | KDM4EHTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL5195645 | 0.84 | PLK1 (0.49) | HTTSMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL4307061 | 0.83 | KDM4E (0.51) | KDM4EHTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL1612288 | 0.83 | LOXL2 (0.54) | KDM4EHTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL2772618 | 0.83 | HTT (0.48) | KDM4EHTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL12505392 | 0.83 | PARP15 (0.54) | KDM4EHTTSMN1; SMN2MAPTNPC1 | |
| SCHEMBL16992587 | 0.83 | KDM4E (0.46) | KDM4EHTTSMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113493449-A | NO donor coumarin furazan conjugate and pharmaceutical application thereof | 复旦大学 | 2021-10-12 | — | — | CN | disclosed |