Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928167 | 1.00 | CASR (0.50) | CASRTDP1TSHRPTPN1L3MBTL1 | |
| SCHEMBL28662971 | 0.90 | CASR (0.61) | CASRTDP1TSHRL3MBTL1MEN1 | |
| SCHEMBL28662969 | 0.90 | CASR (0.61) | CASRTDP1TSHRL3MBTL1MEN1 | |
| SCHEMBL28663869 | 0.88 | TDP1 (0.59) | CASRTDP1TSHRL3MBTL1MEN1 | |
| SCHEMBL28663870 | 0.88 | TDP1 (0.59) | CASRTDP1TSHRL3MBTL1MEN1 | |
| SCHEMBL28657560 | 0.82 | SLC6A2 (0.50) | TDP1L3MBTL1MEN1KMT2ASLC10A1 | |
| SCHEMBL28657559 | 0.82 | SLC6A2 (0.50) | TDP1L3MBTL1MEN1KMT2ASLC10A1 | |
| SCHEMBL28666566 | 0.77 | MYC (0.40) | TACR1 | |
| SCHEMBL28669067 | 0.76 | AKT1 (0.46) | L3MBTL1MEN1KMT2ADRD2 | |
| SCHEMBL28669069 | 0.76 | AKT1 (0.46) | L3MBTL1MEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683556-B | Chiral aryl N-heteroaryl methylamine and preparation method thereof | 湖北滋兰生物医药科技有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-113683556-A | Chiral aryl N-heteroaryl methylamine and preparation method thereof | 湖北滋兰生物医药科技有限公司 | 2021-11-23 | — | — | CN | disclosed |