Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK1 | P51617 | 2/20 | 0.56 |
| ▸ | CDK14 | O94921 | 5/20 | 0.55 |
| ▸ | CCNY | Q8ND76 | 5/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.54 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 2/20 | 0.53 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.53 |
| ▸ | PIP4K2A | P48426 | 4/20 | 0.52 |
| ▸ | PIP4K2B | P78356 | 4/20 | 0.52 |
| ▸ | CDK7 | P50613 | 2/20 | 0.50 |
| ▸ | CCNH | P51946 | 1/20 | 0.50 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | CDK9 | P50750 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.49 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30716322 | 0.87 | CREBBP (0.55) | IRAK1CDK14CCNYMAPK8MAPK9 | |
| SCHEMBL26696904 | 0.87 | CREBBP (0.55) | IRAK1CDK14CCNYMAPK8MAPK9 | |
| SCHEMBL26696906 | 0.87 | CREBBP (0.55) | IRAK1CDK14CCNYMAPK8MAPK9 | |
| SCHEMBL30731007 | 0.86 | PARP1 (0.65) | IRAK1CDK14CCNYMAPK8MAPK9 | |
| SCHEMBL31069490 | 0.86 | PARP1 (0.65) | IRAK1CDK14CCNYMAPK8MAPK9 | |
| SCHEMBL21282715 | 0.85 | IRAK1 (0.57) | IRAK1CDK14CCNYMAPK8MAPK9 | |
| SCHEMBL28421380 | 0.85 | IRAK1 (0.57) | IRAK1CDK14CCNYMAPK8MAPK9 | |
| SCHEMBL18069738 | 0.84 | PIP4K2A (0.53) | IRAK1CDK14CCNYMAPK8MAPK9 | |
| SCHEMBL27461825 | 0.84 | PARP1 (0.52) | IRAK1CDK14CCNYMAPK8MAPK9 | |
| SCHEMBL21481529 | 0.83 | IRAK1 (0.55) | IRAK1CDK14CCNYMAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | claimed |
| CN-113498342-A | Compounds involved in synergistic binding and uses thereof | 锐新医药公司 | 2021-10-12 | — | — | CN | disclosed |