SCHEMBL28928320

SCHEMBL28928320

CC(Cn1cnc2c(N)ncnc21)OC(C(C)(C)C)(C(C)(C)C)P(=O)(O)O

nearest known ligand 0.66

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 14/20 0.66
ADORA2A P29274 1/20 0.56
ADORA1 P30542 1/20 0.56
CYP2D6 P10635 14/20 0.55
FAP Q12884 1/20 0.52
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29930426 1.00 CYP3A4 (0.66) CYP3A4ADORA2AADORA1CYP2D6FAP
SCHEMBL2578605 0.86 CYP3A4 (0.67) CYP3A4ADORA2AADORA1CYP2D6FAP
SCHEMBL2582709 0.86 CYP3A4 (0.67) CYP3A4ADORA2AADORA1CYP2D6FAP
SCHEMBL20302996 0.86 CYP3A4 (0.67) CYP3A4ADORA2AADORA1CYP2D6FAP
Hydrochloric Acid SCHEMBL19603087 0.85 CYP3A4 (0.66) CYP3A4ADORA2AADORA1CYP2D6FAP
SCHEMBL28394183 0.84 CYP3A4 (0.65) CYP3A4ADORA2AADORA1CYP2D6FAP
SCHEMBL19229982 0.84 CYP3A4 (0.65) CYP3A4ADORA2AADORA1CYP2D6FAP
SCHEMBL22131060 0.82 ADORA2A (0.64) CYP3A4ADORA2AADORA1CYP2D6FAP
SCHEMBL14969422 0.82 CYP3A4 (0.62) CYP3A4ADORA2AADORA1CYP2D6FAP
SCHEMBL14969423 0.82 CYP3A4 (0.62) CYP3A4ADORA2AADORA1CYP2D6FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113214322-B Green and environment-friendly preparation method of tenofovir 山东立新制药有限公司 2022-10-25 CN disclosed
CN-113214322-A Green and environment-friendly preparation method of tenofovir 山东立新制药有限公司 2021-08-06 CN disclosed