Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 14/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 13/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.55 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.55 |
| ▸ | FAP | Q12884 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2582709 | 0.87 | CYP3A4 (0.67) | CYP3A4CYP2D6ADORA2AADORA1FAP | |
| SCHEMBL2578605 | 0.87 | CYP3A4 (0.67) | CYP3A4CYP2D6ADORA2AADORA1FAP | |
| SCHEMBL20302996 | 0.85 | CYP3A4 (0.67) | CYP3A4CYP2D6ADORA2AADORA1FAP | |
| Hydrochloric Acid SCHEMBL19603087 | 0.84 | CYP3A4 (0.66) | CYP3A4CYP2D6ADORA2AADORA1FAP | |
| SCHEMBL28928320 | 0.84 | CYP3A4 (0.66) | CYP3A4CYP2D6ADORA2AADORA1FAP | |
| SCHEMBL29930426 | 0.84 | CYP3A4 (0.66) | CYP3A4CYP2D6ADORA2AADORA1FAP | |
| SCHEMBL19229982 | 0.83 | CYP3A4 (0.65) | CYP3A4CYP2D6ADORA2AADORA1FAP | |
| SCHEMBL8397115 | 0.83 | FGFR1 (0.61) | CYP3A4ADORA2AADORA1FAP | |
| SCHEMBL14969423 | 0.81 | CYP3A4 (0.62) | CYP3A4CYP2D6ADORA2AADORA1FAP | |
| SCHEMBL14969422 | 0.81 | CYP3A4 (0.62) | CYP3A4CYP2D6ADORA2AADORA1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114409706-B | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2023-11-28 | — | — | CN | disclosed |
| CN-115677774-A | Phosphonate derivatives, their preparation and use | 上海医药工业研究院有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-114409706-A | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2022-04-29 | — | — | CN | disclosed |
| CN-112175003-B | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2022-02-15 | — | — | CN | disclosed |
| CN-112175003-A | Preparation method of phenyl hydrogen phosphonate and intermediate thereof | 上海医药工业研究院 | 2021-01-05 | — | — | CN | disclosed |
| CN-107941956-B | High performance liquid chromatography analysis and detection method for tenofovir and enantiomer thereof | 湖北丽益医药科技有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-108586532-B | Preparation method of tenofovir disoproxil fumarate | 科兴生物制药股份有限公司 | 2020-05-08 | — | — | CN | disclosed |