Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.52 |
| ▸ | SYK | P43405 | 4/20 | 0.52 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RGS12 | O14924 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BCL2A1 | Q16548 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610930 | 0.94 | PPARA (0.57) | PPARASTING1SYKKDM4CLCK | |
| SCHEMBL29391594 | 0.94 | PPARA (0.57) | PPARASTING1SYKKDM4CLCK | |
| SCHEMBL610123 | 0.93 | SYK (0.58) | PPARASTING1SYKKDM4CCA1 | |
| SCHEMBL29388077 | 0.93 | SYK (0.58) | PPARASTING1SYKKDM4CCA1 | |
| SCHEMBL28928407 | 0.90 | SYK (0.46) | PPARASTING1SYKKDM4CMAPT | |
| SCHEMBL29391568 | 0.83 | KDM4C (0.53) | PPARASTING1SYKKDM4CLCK | |
| SCHEMBL610065 | 0.83 | KDM4C (0.53) | PPARASTING1SYKKDM4CLCK | |
| SCHEMBL4097800 | 0.81 | PPARA (0.52) | PPARASTING1SYKKDM4CLCK | |
| SCHEMBL4095655 | 0.81 | PPARA (0.52) | PPARASTING1SYKKDM4CLCK | |
| SCHEMBL608754 | 0.81 | NOX4 (0.61) | PPARASTING1SYKKDM4CLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113710242-A | Compositions and methods for treating neurodegenerative disorders | 吉恩特药业株式会社 | 2021-11-26 | — | — | CN | claimed |