Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.45 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.45 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | TTK | P33981 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | NEK2 | P51955 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226279 | 0.80 | MCL1 (0.45) | MCL1FGFR1DDR2MAP3K7TAB1 | |
| SCHEMBL13739332 | 0.78 | RXRA (0.54) | MCL1FGFR1DDR2KDM5BRXRA | |
| SCHEMBL26132700 | 0.77 | MCL1 (0.40) | MCL1FGFR1DDR2MAP3K7TAB1 | |
| SCHEMBL30582740 | 0.77 | MCL1 (0.43) | MCL1FGFR1DDR2ALDH1A1KDM5B | |
| SCHEMBL25225221 | 0.77 | FGFR1 (0.49) | MCL1FGFR1MAP3K7TAB1SMN1; SMN2 | |
| SCHEMBL28483450 | 0.77 | MCL1 (0.49) | MCL1FGFR1DDR2CYP3A4SMN1; SMN2 | |
| SCHEMBL19029753 | 0.76 | MCL1 (0.45) | MCL1FGFR1DDR2MEN1KMT2A | |
| SCHEMBL29533406 | 0.75 | KDM5B (0.47) | MCL1FGFR1DDR2PIK3CAPIK3CD | |
| SCHEMBL24892395 | 0.75 | MCL1 (0.40) | MCL1FGFR1DDR2MAPTAAK1 | |
| SCHEMBL23535723 | 0.74 | MCL1 (0.45) | MCL1FGFR1DDR2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113692276-A | NURR1 receptor modulators | 加利福尼亚大学董事会 | 2021-11-23 | — | — | CN | disclosed |