Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 20/20 | 0.75 |
| ▸ | HCRTR2 | O43614 | 20/20 | 0.75 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16638936 | 0.90 | HCRTR1 (0.74) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL26350983 | 0.90 | HCRTR1 (0.74) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL26351279 | 0.90 | HCRTR1 (0.74) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL26350991 | 0.90 | HCRTR1 (0.74) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2610558 | 0.90 | HCRTR1 (0.74) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL24533939 | 0.90 | HCRTR1 (0.74) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL29521524 | 0.90 | HCRTR1 (0.74) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL2116763 | 0.90 | HCRTR1 (0.74) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL22666388 | 0.90 | HCRTR1 (0.74) | HCRTR1HCRTR2KCNH2 | |
| SCHEMBL26350998 | 0.89 | HCRTR1 (0.73) | HCRTR1HCRTR2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113727962-A | Methods and compounds for preparing orexin-2 receptor antagonists and lebereproduction with reduced impurities | 卫材R&D管理有限公司 | 2021-11-30 | — | — | CN | disclosed |