Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 10/20 | 0.71 |
| ▸ | ABL1 | P00519 | 9/20 | 0.71 |
| ▸ | ABL2 | P42684 | 9/20 | 0.71 |
| ▸ | SRC | P12931 | 11/20 | 0.71 |
| ▸ | RIPK2 | O43353 | 6/20 | 0.69 |
| ▸ | LCK | P06239 | 3/20 | 0.66 |
| ▸ | KDR | P35968 | 3/20 | 0.66 |
| ▸ | TEK | Q02763 | 3/20 | 0.66 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.66 |
| ▸ | PRKCG | P05129 | 1/20 | 0.66 |
| ▸ | PRKCB | P05771 | 1/20 | 0.66 |
| ▸ | PRKCA | P17252 | 1/20 | 0.66 |
| ▸ | PRKCH | P24723 | 1/20 | 0.66 |
| ▸ | PRKCI | P41743 | 1/20 | 0.66 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.66 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.66 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.66 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.66 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928810 | 1.00 | EGFR (0.71) | EGFRABL1ABL2SRCRIPK2 | |
| SCHEMBL20351628 | 0.94 | SRC (0.80) | EGFRABL1ABL2SRCRIPK2 | |
| SCHEMBL18044541 | 0.89 | SRC (0.81) | EGFRABL1ABL2SRCRIPK2 | |
| SCHEMBL28669568 | 0.88 | EGFR (0.56) | EGFRABL1ABL2SRCRIPK2 | |
| SCHEMBL28669572 | 0.88 | EGFR (0.56) | EGFRABL1ABL2SRCRIPK2 | |
| SCHEMBL2075318 | 0.86 | SRC (0.89) | EGFRABL1ABL2SRCLCK | |
| SCHEMBL20351800 | 0.85 | SRC (0.74) | EGFRABL1ABL2SRCRIPK2 | |
| SCHEMBL20351777 | 0.84 | SRC (0.66) | EGFRABL1ABL2SRCRIPK2 | |
| SCHEMBL8930209 | 0.83 | EGFR (1.00) | EGFRABL1ABL2SRCRIPK2 | |
| SCHEMBL16752298 | 0.83 | SRC (0.77) | EGFRABL1ABL2SRCRIPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683629-B | Substituted heteroaryl compounds, compositions and uses thereof | 北京范恩柯尔生物科技有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-113683629-A | Substituted heteroaryl compounds, compositions and uses thereof | 北京范恩柯尔生物科技有限公司 | 2021-11-23 | — | — | CN | disclosed |