Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 5/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.32 |
| ▸ | FABP3 | P05413 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | PRNP | P04156 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928898 | 0.87 | POLB (0.44) | POLBMEN1KMT2AFABP4FABP3 | |
| SCHEMBL28929449 | 0.81 | PRNP (0.40) | MEN1KMT2AFABP4FABP5FABP3 | |
| SCHEMBL28994151 | 0.79 | HSD17B10 (0.38) | TP53KDM4EALDH1A1LMNAGAA | |
| SCHEMBL25117842 | 0.79 | MAPT (0.48) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL28928926 | 0.69 | PRNP (0.38) | MEN1KMT2AFABP4FABP5FABP3 | |
| SCHEMBL25171145 | 0.69 | KDM4E (0.37) | TP53KDM4EALDH1A1LMNAGAA | |
| SCHEMBL25117860 | 0.69 | ALDH1A1 (0.54) | MEN1KMT2AKDM4EALDH1A1LMNA | |
| SCHEMBL28928909 | 0.66 | MEN1 (0.46) | POLBMEN1KMT2AFABP4FABP3 | |
| SCHEMBL30309821 | 0.65 | NPC1 (0.44) | POLBMEN1KMT2ATHRBKDM4E | |
| SCHEMBL25414951 | 0.63 | PDE11A (0.36) | POLBMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113754682-B | Compound having macrocyclic structure and use thereof | 赛诺哈勃药业（成都）有限公司 | 2023-01-06 | — | — | CN | disclosed |
| CN-113754682-A | Compounds having macrocyclic structure and uses thereof | 成都倍特药业股份有限公司 | 2021-12-07 | — | — | CN | disclosed |