SCHEMBL28929901

SCHEMBL28929901

FC(F)(F)c1nc(-c2cc[c]c(Oc3c(Cl)cccc3Cl)c2)no1

nearest known ligand 0.47

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HDAC6 Q9UBN7 18/20 0.47
HDAC1 Q13547 14/20 0.47
HDAC4 P56524 6/20 0.43
HDAC8 Q9BY41 6/20 0.41
HDAC5 Q9UQL6 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28673450 0.85 HDAC6 (0.46) HDAC6HDAC1HDAC4HDAC8HDAC5
SCHEMBL28678985 0.84 HDAC6 (0.41) HDAC6HDAC1HDAC4HDAC8HDAC5
SCHEMBL28654893 0.84 HDAC6 (0.44) HDAC6HDAC1HDAC4HDAC8HDAC5
SCHEMBL28671183 0.83 HDAC6 (0.53) HDAC6HDAC1HDAC4HDAC8HDAC5
SCHEMBL28675062 0.83 SMN1; SMN2 (0.40) HDAC6HDAC1HDAC8HDAC5
SCHEMBL28673816 0.83 MAPT (0.41) HDAC6HDAC1HDAC4HDAC8HDAC5
SCHEMBL28669788 0.82 HDAC6 (0.42) HDAC6HDAC1HDAC4HDAC8HDAC5
SCHEMBL28659409 0.82 HDAC1 (0.45) HDAC6HDAC1HDAC4HDAC8HDAC5
SCHEMBL28681727 0.82 CASP3 (0.43) HDAC6HDAC1HDAC4HDAC8HDAC5
SCHEMBL28659108 0.82 HDAC6 (0.47) HDAC6HDAC1HDAC4HDAC8HDAC5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113784958-B Oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2024-04-30 CN claimed
CN-113784958-A Novel oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2021-12-10 CN claimed
CN-113784958-B Oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2024-04-30 CN disclosed
CN-113784958-A Novel oxadiazole compounds for controlling or preventing phytopathogenic fungi PI工业有限公司 2021-12-10 CN disclosed