Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CCNC | P24863 | 2/20 | 0.41 |
| ▸ | CDK8 | P49336 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27185413 | 0.85 | TSHR (0.47) | TSHRKDM5AKDM5BTP53CASP1 | |
| SCHEMBL28671837 | 0.84 | TSHR (0.46) | TSHRKDM5AKDM5BTP53CASP1 | |
| SCHEMBL6386138 | 0.83 | TSHR (0.47) | TSHRTP53CASP1NPSR1CCNC | |
| SCHEMBL6386142 | 0.83 | TSHR (0.47) | TSHRTP53CASP1NPSR1CCNC | |
| Bromide SCHEMBL25305290 | 0.81 | SRC (0.40) | TSHRKDM5AKDM5BTP53CASP1 | |
| SCHEMBL6387535 | 0.81 | TSHR (0.45) | TSHRTP53NPSR1CCNCCDK8 | |
| SCHEMBL6387533 | 0.81 | TSHR (0.45) | TSHRTP53NPSR1CCNCCDK8 | |
| SCHEMBL29837473 | 0.79 | TSHR (0.60) | TSHRKDM5AKDM5BTP53CASP1 | |
| SCHEMBL3515887 | 0.79 | TSHR (0.60) | TSHRKDM5AKDM5BTP53CASP1 | |
| SCHEMBL29570949 | 0.78 | SIRT3 (0.58) | TSHRKDM5AKDM5BTP53CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433210-A | Preparation and application of compound with immunoregulation function | 上海轶诺药业有限公司 | 2022-12-06 | — | — | CN | disclosed |