Isoxazole

Isoxazole

SCHEMBL28930409

NC(N)=S.c1cnoc1

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoxazole SCHEMBL28669733 0.97 PARP1 (0.65)
Isoxazole SCHEMBL11568599 0.84
Isoxazole SCHEMBL28926974 0.83
Isoxazole SCHEMBL27586002 0.83
Isoxazole SCHEMBL2679369 0.83 PARP1 (1.00)
Isoxazole SCHEMBL393230 0.83
Isoxazole SCHEMBL1318 0.83
Isoxazole SCHEMBL442195 0.82
Isoxazole SCHEMBL22495126 0.80
Isoxazole SCHEMBL28782251 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307533-A Preparation method of pyrazophos 浙江中山化工集团股份有限公司 2024-07-09 CN claimed
CN-117924265-A Synthesis method of pyrifos 潍坊新绿化工有限公司 2024-04-26 CN claimed
CN-113831333-B Synthesis method of pyrifos 大连九信精细化工有限公司 2023-07-28 CN claimed
CN-113831333-A Synthetic method of sulfuryl pyraflufen 大连九信精细化工有限公司 2021-12-24 CN claimed
CN-119798245-A Synthesis method and application of pyrifos-methyl 内蒙古永太化学有限公司 2025-04-11 CN disclosed
CN-119504590-A 1-Methyl-3-trifluoromethyl-4-chloromethyl-5-difluoromethoxy-1-H-pyrazole and preparation method thereof 鹤壁市宝瑞德化工有限公司 2025-02-25 CN disclosed
CN-119431352-A Sulfopyrrole (L.) Harf Process for preparing azoles 浙江中山化工集团股份有限公司 2025-02-14 CN disclosed
CN-118359541-A Preparation method of haloxyfop-methyl 潍坊中农联合化工有限公司 2024-07-19 CN disclosed
CN-118307533-A Preparation method of pyrazophos 浙江中山化工集团股份有限公司 2024-07-09 CN disclosed
CN-118307533-A Preparation method of pyrazophos 浙江中山化工集团股份有限公司 2024-07-09 CN disclosed
CN-117924265-A Synthesis method of pyrifos 潍坊新绿化工有限公司 2024-04-26 CN disclosed
CN-117924265-A Synthesis method of pyrifos 潍坊新绿化工有限公司 2024-04-26 CN disclosed
CN-113831333-B Synthesis method of pyrifos 大连九信精细化工有限公司 2023-07-28 CN disclosed
CN-113831333-B Synthesis method of pyrifos 大连九信精细化工有限公司 2023-07-28 CN disclosed
CN-113831333-A Synthetic method of sulfuryl pyraflufen 大连九信精细化工有限公司 2021-12-24 CN disclosed
CN-113831333-A Synthetic method of sulfuryl pyraflufen 大连九信精细化工有限公司 2021-12-24 CN disclosed