Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22897861 | 0.91 | KDM4E (0.44) | MAPTMAPK1KDM4ENPC1MITF | |
| SCHEMBL22897907 | 0.85 | ALDH1A1 (0.43) | MAPTMAPK1KDM4ENPC1MITF | |
| SCHEMBL22897846 | 0.83 | MALT1 (0.42) | MAPTKDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL29559840 | 0.80 | ALDH1A1 (0.51) | MAPTMAPK1KDM4ENPC1MITF | |
| SCHEMBL28694139 | 0.80 | ALDH1A1 (0.55) | MAPTMAPK1KDM4ENPC1MITF | |
| SCHEMBL22897508 | 0.80 | ALDH1A1 (0.51) | MAPTMAPK1KDM4ENPC1MITF | |
| SCHEMBL24534304 | 0.79 | ALDH1A1 (0.47) | MAPTMAPK1KDM4ENPC1RAB9A | |
| SCHEMBL22897749 | 0.79 | AR (0.38) | MAPTMAPK1KDM4ENPC1MITF | |
| SCHEMBL22897925 | 0.78 | ALDH1A1 (0.40) | MAPTMAPK1KDM4ENPC1MITF | |
| SCHEMBL22897918 | 0.76 | ALDH1A1 (0.47) | MAPTKDM4ENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114072000-A | Molecules having certain pesticidal effects and intermediates, compositions and methods related thereto | 科迪华农业科技有限责任公司 | 2022-02-18 | — | — | CN | disclosed |