Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20917419 | 0.77 | TDP1 (0.52) | TDP1L3MBTL1TSHRMEN1LMNA | |
| SCHEMBL8862878 | 0.76 | TDP1 (0.75) | TDP1L3MBTL1MEN1KMT2AHDAC8 | |
| SCHEMBL8863094 | 0.76 | TDP1 (0.75) | TDP1L3MBTL1MEN1KMT2AHDAC8 | |
| SCHEMBL6777483 | 0.76 | TDP1 (0.75) | TDP1L3MBTL1MEN1KMT2AHDAC8 | |
| SCHEMBL8862728 | 0.76 | TDP1 (0.75) | TDP1L3MBTL1MEN1KMT2AHDAC8 | |
| SCHEMBL2604742 | 0.76 | TDP1 (0.75) | TDP1L3MBTL1MEN1KMT2AHDAC8 | |
| SCHEMBL8863154 | 0.76 | TDP1 (0.75) | TDP1L3MBTL1MEN1KMT2AHDAC8 | |
| SCHEMBL29263710 | 0.76 | TDP1 (0.57) | TDP1L3MBTL1TSHRMEN1LMNA | |
| SCHEMBL29263618 | 0.75 | HSD17B10 (0.77) | TDP1L3MBTL1TSHRMEN1LMNA | |
| SCHEMBL6790333 | 0.74 | TDP1 (0.71) | TDP1L3MBTL1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113943276-A | Nitrogen heterocyclic compound and application thereof | 武汉人福创新药物研发中心有限公司 | 2022-01-18 | — | — | CN | disclosed |