Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | GLS | O94925 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.62 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.62 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.62 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.62 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2604742 | 0.98 | TDP1 (0.75) | TDP1L3MBTL1CYP1A2CYP2C19MEN1 | |
| SCHEMBL8863094 | 0.98 | TDP1 (0.75) | TDP1L3MBTL1CYP1A2CYP2C19MEN1 | |
| SCHEMBL8862878 | 0.98 | TDP1 (0.75) | TDP1L3MBTL1CYP1A2CYP2C19MEN1 | |
| SCHEMBL6777483 | 0.98 | TDP1 (0.75) | TDP1L3MBTL1CYP1A2CYP2C19MEN1 | |
| SCHEMBL8862728 | 0.98 | TDP1 (0.75) | TDP1L3MBTL1CYP1A2CYP2C19MEN1 | |
| SCHEMBL8863154 | 0.98 | TDP1 (0.75) | TDP1L3MBTL1CYP1A2CYP2C19MEN1 | |
| SCHEMBL4351612 | 0.95 | TDP1 (0.66) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL7349638 | 0.91 | TDP1 (0.62) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6699936 | 0.90 | GLS (0.71) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3009266 | 0.89 | TDP1 (0.61) | TDP1L3MBTL1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688312-A | INKS WITH COLORS AND IMIDES OR BISIMIDES, FOR ACOUSTIC INK PRINTER AND DROP EJECTOR | XEROX CORPORATION (US) | 1997-11-18 | — | — | US | claimed |
| EP-0220409-B1 | GEM-DIHALO AND TETRAHALO-1,12-DIAMINO-4,9-DIAZA-DODECANES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1991-11-27 | — | — | EP | claimed |
| EP-0220409-A2 | Gem-dihalo and tetrahalo-1,12-diamino-4,9-diaza-dodecanes | MERRELL DOW PHARMACEUTICALS INC. (US) | 1987-05-06 | — | — | EP | claimed |
| US-4517315-A | Production of a film-like or fibrous structure of an aromatic polyester | TEIJIN LIMITED (JP) | 1985-05-14 | — | — | US | claimed |
| CN-114539070-B | Method for preparing 1,4-butanediamine from 1, 4-butanedioic acid | 中国科学院大连化学物理研究所 | 2023-03-03 | — | — | CN | disclosed |
| EP-3190122-A1 | A NOVEL SYNTHETIC PATHWAY TOWARDS SOLITHROMYCIN AND PURIFICATION THEREOF | LEK Pharmaceuticals d.d. (SI) | 2017-07-12 | — | — | EP | disclosed |
| CN-101735067-B | Synthesis method of 1,4-butanediamine | UNIV ZHEJIANG TECHNOLOGY | 2013-01-16 | — | — | CN | disclosed |
| CN-101735067-A | Synthesis method of 1,4-butanediamine | UNIV ZHEJIANG TECHNOLOGY | 2010-06-16 | — | — | CN | disclosed |
| US-20040176612-A1 | Method for preparing n-($g(v)-bromoalkyl)phthalimides | GILLET JEAN-PHILIPPE (FR) | 2004-09-09 | — | — | US | disclosed |
| US-5688312-A | INKS WITH COLORS AND IMIDES OR BISIMIDES, FOR ACOUSTIC INK PRINTER AND DROP EJECTOR | XEROX CORPORATION (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0210851-B1 | Mixtures of polyamideimides, containing 3,4'-diaminodiphenylether as diamine component, and of a plasticizer. | TEIJIN LIMITED (JP) | 1992-03-18 | — | — | EP | disclosed |
| EP-0156966-B1 | WHOLLY AROMATIC POLYESTER COMPOSITION AND PROCESS FOR PRODUCING IT | TEIJIN LIMITED (JP) | 1988-10-19 | — | — | EP | disclosed |
| EP-0057387-B1 | PRODUCTION OF A FILM-LIKE OR FIBROUS STRUCTURE OF AN AROMATIC POLYESTER | TEIJIN LIMITED (JP) | 1986-05-07 | — | — | EP | disclosed |
| EP-0156966-A1 | Wholly aromatic polyester composition and process for producing it | TEIJIN LIMITED (JP) | 1985-10-09 | — | — | EP | disclosed |
| US-4517315-A | Production of a film-like or fibrous structure of an aromatic polyester | TEIJIN LIMITED (JP) | 1985-05-14 | — | — | US | disclosed |
| US-4419308-A | SOLVENT EXTRACTION OF IMIDE OR ISOCYANURATE | TEIJIN LIMITED (JP) | 1983-12-06 | — | — | US | disclosed |
| US-4416839-A | Wholly aromatic polyester composition, process for production thereof, and production therefrom of a film-like or fibrous article of a wholly aromatic polyester | TEIJIN LIMITED (JP) | 1983-11-22 | — | — | US | disclosed |
| EP-0091669-A2 | Process for producing porous, film-like or fibrous structure of aromatic polyester | TEIJIN LIMITED (JP) | 1983-10-19 | — | — | EP | disclosed |
| EP-0070539-A1 | Process for producing a film-like and fibrous article of a wholly aromatic polyester | TEIJIN LIMITED (JP) | 1983-01-26 | — | — | EP | disclosed |
| EP-0057387-A2 | Production of a film-like or fibrous structure of an aromatic polyester | TEIJIN LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040176612-A1 | Method for preparing n-($g(v)-bromoalkyl)phthalimides | GK, DGKA, GNG2 | TDP1 3482/4885L3MBTL1 3639/4885MAPT 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.