Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Allyl Alcohol SCHEMBL28393750 | 0.89 | TDP1 (0.55) | TDP1ALDH1A1NR1I2TAS1R3TAS1R1 | |
| SCHEMBL19915134 | 0.88 | TDP1 (0.61) | TDP1ALDH1A1NR1I2LMNAPTGS2 | |
| SCHEMBL94887 | 0.88 | TDP1 (0.61) | TDP1ALDH1A1NR1I2LMNAPTGS2 | |
| Water SCHEMBL17044655 | 0.86 | TDP1 (0.59) | TDP1ALDH1A1NR1I2LMNAPTGS2 | |
| SCHEMBL6035161 | 0.86 | TDP1 (0.59) | TDP1ALDH1A1NR1I2LMNAPTGS2 | |
| Water SCHEMBL2898586 | 0.86 | TDP1 (0.59) | TDP1ALDH1A1NR1I2LMNAPTGS2 | |
| Potassium Ion SCHEMBL331671 | 0.84 | TDP1 (0.61) | TDP1ALDH1A1LMNAPTGS2MCL1 | |
| SCHEMBL2024117 | 0.84 | TDP1 (0.61) | TDP1ALDH1A1LMNAPTGS2MCL1 | |
| SCHEMBL2025169 | 0.84 | TDP1 (0.61) | TDP1ALDH1A1LMNAPTGS2MCL1 | |
| Lithium Ion SCHEMBL813502 | 0.84 | TDP1 (0.61) | TDP1ALDH1A1LMNAPTGS2MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114075310-B | Two-phase viscosity regulator and preparation method thereof | 中国石油化工股份有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-114075310-A | Two-phase viscosity regulator and preparation method thereof | 中国石油化工股份有限公司 | 2022-02-22 | — | — | CN | claimed |
| CN-114075310-B | Two-phase viscosity regulator and preparation method thereof | 中国石油化工股份有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-114075310-A | Two-phase viscosity regulator and preparation method thereof | 中国石油化工股份有限公司 | 2022-02-22 | — | — | CN | disclosed |