Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 known ✓ | Q9BY41 | 1/20 | 0.33 |
| ▸ | PTGS2 known ✓ | P35354 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.32 |
| ▸ | DUSP6 | Q16828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL17044655 | 1.00 | TDP1 (0.59) | TDP1ALDH1A1LMNATSHRPLCG1 | |
| SCHEMBL94887 | 0.98 | TDP1 (0.61) | TDP1ALDH1A1LMNATSHRPLCG1 | |
| SCHEMBL19915134 | 0.98 | TDP1 (0.61) | TDP1ALDH1A1LMNATSHRPLCG1 | |
| SCHEMBL6035161 | 0.95 | TDP1 (0.59) | TDP1ALDH1A1LMNATSHRPLCG1 | |
| SCHEMBL5621482 | 0.93 | TDP1 (0.61) | TDP1ALDH1A1LMNATSHRPLCG1 | |
| SCHEMBL2023060 | 0.93 | TDP1 (0.61) | TDP1ALDH1A1LMNATSHRPLCG1 | |
| Potassium Ion SCHEMBL331671 | 0.93 | TDP1 (0.61) | TDP1ALDH1A1LMNATSHRPLCG1 | |
| SCHEMBL2025169 | 0.93 | TDP1 (0.61) | TDP1ALDH1A1LMNATSHRPLCG1 | |
| SCHEMBL17476623 | 0.93 | TDP1 (0.61) | TDP1ALDH1A1LMNATSHRPLCG1 | |
| SCHEMBL2024117 | 0.93 | TDP1 (0.61) | TDP1ALDH1A1LMNATSHRPLCG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540297-A1 | PHOTOCURABLE COMPOSITIONS AND METHODS FOR DELIVERING RADIATION TO A SUBJECT | Theragenics Corporation (US) | 2025-04-23 | — | — | EP | claimed |
| CN-118085654-B | UV (ultraviolet) curing coating and preparation method and application thereof | 广东欣创新材料科技有限公司 | 2024-07-16 | — | — | CN | claimed |
| US-20240207456-A1 | PHOTOCURABLE COMPOSITIONS AND METHODS FOR DELIVERING RADIATION TO A SUBJECT | AQUARIAN CREDIT FUNDING LLC | 2024-06-27 | — | — | US | claimed |
| CN-118085654-A | UV (ultraviolet) curing coating and preparation method and application thereof | 广东欣创新材料科技有限公司 | 2024-05-28 | — | — | CN | claimed |
| WO-2023245093-A1 | PHOTOCURABLE COMPOSITIONS AND METHODS FOR DELIVERING RADIATION TO A SUBJECT | THERAGENICS CORPORATION (US) | 2023-12-21 | — | — | WO | claimed |
| CN-114957567-B | Method for grafting sodium p-styryl sulfonate monomer by polyether-ether-ketone and application | 北京大学南昌创新研究院 | 2023-12-01 | — | — | CN | claimed |
| CN-114957567-A | Method for grafting sodium p-styrenesulfonate monomer on polyether-ether-ketone and application | 北京大学南昌创新研究院 | 2022-08-30 | — | — | CN | claimed |
| CN-109699180-B | Cell co-culture chip and preparation method thereof | 格勒诺布尔-阿尔卑斯大学 | 2022-07-26 | — | — | CN | claimed |
| CN-113265026-B | Water-swelling rubber flexible temporary plugging particle and preparation method thereof | 西南石油大学 | 2022-04-12 | — | — | CN | claimed |
| CN-112979892-B | Ion conductive gel and preparation method thereof | 中国科学院大连化学物理研究所 | 2022-04-01 | — | — | CN | claimed |
| CN-113265026-A | Water-swelling rubber flexible temporary plugging particle and preparation method thereof | 西南石油大学 | 2021-08-17 | — | — | CN | claimed |
| CN-112979892-A | Ion conductive gel and preparation method thereof | 中国科学院大连化学物理研究所 | 2021-06-18 | — | — | CN | claimed |
| CN-112986338-A | Hydrogel gas sensor, gas detection device and gas detection method | 中国科学院大连化学物理研究所 | 2021-06-18 | — | — | CN | claimed |
| CN-121824028-A | PVA fiber-containing anti-compression geopolymer material and preparation method thereof | 江苏国泓建设工程有限公司 | 2026-04-10 | — | — | CN | disclosed |
| US-20250332325-A1 | DOUBLE NETWORK HYDROGEL WITH ANIONIC POLYMER AND USES THEREOF | POLY MED INC (US) | 2025-10-30 | — | — | US | disclosed |
| US-12370289-B2 | Double network hydrogel with anionic polymer and uses thereof | POLY-MED, INC. (US) | 2025-07-29 | — | — | US | disclosed |
| US-20100316955-A1 | CHEMICALLY AMPLIFIED POSITIVE PHOTORESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2010-12-16 | — | — | US | disclosed |
| US-20090011929-A1 | MULTINUCLEAR COMPLEX AND POLYMER THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-01-08 | — | — | US | disclosed |
| EP-1988082-A1 | POLYNUCLEAR COMPLEX AND POLYMER THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-20060052559-A1 | Insoluble, highly cross-linked popcorn polymers containing styrene-4-sulfonate methods for the production and use thereof | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090011929-A1 | MULTINUCLEAR COMPLEX AND POLYMER THEREOF | PICALM, PARG, PCBP1 | HDAC8 2787/4885PTGS2 3485/4885TDP1 3903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.