Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28709574 | 0.86 | MAPT (0.32) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL29431904 | 0.78 | LRRK2 (0.33) | KDM4EMAPTCCNT1CDK9CRBN | |
| SCHEMBL29431921 | 0.73 | LRRK2 (0.33) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL18879715 | 0.68 | MAPT (0.40) | KDM4EALDH1A1MAPT | |
| SCHEMBL28700084 | 0.67 | FFAR4 (0.33) | MAPT | |
| SCHEMBL29431923 | 0.67 | ALK (0.38) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL28729215 | 0.66 | KDM4E (0.47) | KDM4EADRA2BMAPK1ALDH1A1HPGD | |
| SCHEMBL29431902 | 0.64 | LRRK2 (0.32) | MAPT | |
| SCHEMBL28700051 | 0.63 | HTR1A (0.34) | KDM4EALDH1A1MAPTCCNT1CDK9 | |
| SCHEMBL4814415 | 0.61 | CRBN (0.49) | KDM4EMAPK1ALDH1A1MAPTCRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113999250-A | Isoleucinine analogue prepared from ofloxacin as raw material, and preparation method and application thereof | 郑州工业应用技术学院 | 2022-02-01 | — | — | CN | claimed |
| CN-113999250-A | Isoleucinine analogue prepared from ofloxacin as raw material, and preparation method and application thereof | 郑州工业应用技术学院 | 2022-02-01 | — | — | CN | disclosed |