SCHEMBL2893423

SCHEMBL2893423

CCCCCCCC/C=C/CC(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 8/20 0.46
CES1 P23141 2/20 0.46
TRPV1 Q8NER1 1/20 0.44
GGPS1 O95749 1/20 0.43
MAPT P10636 3/20 0.40
BLM P54132 3/20 0.40
ALDH1A1 P00352 1/20 0.40
PLA2G4B P0C869 1/20 0.40
PLA2G4A P47712 1/20 0.40
MGLL Q99685 1/20 0.40
PLA2G4C Q9UP65 1/20 0.40
TERT O14746 3/20 0.39
PTPN1 P18031 3/20 0.39
PPARG P37231 3/20 0.39
PPARD Q03181 3/20 0.39
PPARA Q07869 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP2C19 P33261 2/20 0.39
HSD17B10 Q99714 2/20 0.39
FABP4 P15090 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2893424 1.00 FAAH (0.46) FAAHCES1TRPV1GGPS1MAPT
SCHEMBL30119921 0.96 GGPS1 (0.43) FAAHCES1TRPV1GGPS1MAPT
SCHEMBL28940930 0.94 FAAH (0.47) FAAHCES1TRPV1GGPS1MAPT
SCHEMBL2887708 0.91 GGPS1 (0.37) FAAHCES1TRPV1GGPS1MAPT
SCHEMBL2887705 0.91 GGPS1 (0.37) FAAHCES1TRPV1GGPS1MAPT
SCHEMBL15869141 0.78 FAAH (0.53) FAAHCES1TRPV1GGPS1MAPT
SCHEMBL29180732 0.78 FAAH (0.53) FAAHCES1TRPV1GGPS1MAPT
SCHEMBL8380159 0.77 FAAH (0.44) FAAHCES1TRPV1MAPTBLM
SCHEMBL9219367 0.77 FAAH (0.44) FAAHCES1TRPV1MAPTBLM
SCHEMBL9220287 0.77 FAAH (0.44) FAAHCES1TRPV1MAPTBLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2102650-B1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AGENCY SCIENCE TECH & RES (SG) 2021-05-19 EP disclosed
US-20170307486-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY SCIENCE TECH & RES (SG) 2017-10-26 US disclosed
US-9581527-B2 Apparatus for processing a sample in a liquid droplet and method of using the same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-02-28 US disclosed
US-20140234873-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2014-08-21 US disclosed
EP-2004328-B1 METHOD FOR PERFORMING A REACTION IN A DROPLET AGENCY SCIENCE TECH & RES (SG) 2014-06-04 EP disclosed
US-20130236377-A1 APPARATUS FOR PERFORMING A REACTION IN A DROPLET AND METHOD OF USING THE SAME KIM NAM YONG (US) 2013-09-12 US disclosed
US-8261598-B2 Apparatus for performing a reaction in a droplet and method of using the same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2012-09-11 US disclosed
US-20100285573-A1 Apparatus for processing a sample in a liquid droplet and method of using the same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2010-11-11 US disclosed
US-20100000304-A1 Apparatus For Performing a Reaction In a Droplet and Method of Using the Same AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (A*STAR) (SG) 2010-01-07 US disclosed
EP-2102650-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME Agency for Science, Technology And Research (SG) 2009-09-23 EP disclosed
WO-2008063135-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-05-29 WO disclosed
WO-2008063136-A1 APPARATUS FOR PROCESSING A SAMPLE IN A LIQUID DROPLET AND METHOD OF USING THE SAME AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2008-05-29 WO disclosed