Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 14/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.39 |
| ▸ | SPR | P35270 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28934436 | 0.87 | ACHE (0.41) | PDE5ASCN9ACRHR1 | |
| SCHEMBL28963081 | 0.86 | SCN9A (0.40) | PDE5ASCN9ACRHR1KIF11 | |
| SCHEMBL31309258 | 0.84 | PDE5A (0.46) | PDE5ASCN9ACRHR1SPR | |
| SCHEMBL28934449 | 0.84 | KDM4E (0.40) | PDE5ASCN9ACRHR1KIF11 | |
| SCHEMBL28934496 | 0.84 | PDE5A (0.46) | PDE5ASCN9ACRHR1 | |
| SCHEMBL28934710 | 0.82 | ACHE (0.41) | PDE5ASCN9ACRHR1 | |
| SCHEMBL28934326 | 0.81 | ACHE (0.36) | PDE5ASCN9ACRHR1 | |
| SCHEMBL30108833 | 0.81 | ACHE (0.36) | PDE5ASCN9ACRHR1 | |
| SCHEMBL28934464 | 0.81 | MAPT (0.40) | CRHR1 | |
| SCHEMBL30181352 | 0.80 | SCN9A (0.46) | PDE5ASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |