⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15496478 | 1.00 | — | — | |
| SCHEMBL150801 | 1.00 | — | — | |
| Bicarbonate SCHEMBL10842820 | 0.84 | LMNA (0.41) | — | |
| SCHEMBL4709040 | 0.82 | — | — | |
| SCHEMBL28790577 | 0.82 | — | — | |
| SCHEMBL5868407 | 0.77 | — | — | |
| SCHEMBL29057337 | 0.77 | LMNA (0.36) | — | |
| SCHEMBL5868406 | 0.77 | — | — | |
| SCHEMBL1346963 | 0.76 | — | — | |
| SCHEMBL2608974 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334275-B1 | HALOCYCLOPROPANATION PROCESSES | CORTEVA AGRISCIENCE LLC (US) | 2026-01-21 | — | — | EP | disclosed |
| CN-117203181-A | Halogenated cyclopropanation process | 科迪华农业科技有限责任公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-109982992-B | Method for preparing eldecalcitol and intermediate for same | 研成精密化学株式会社 | 2022-05-17 | — | — | CN | disclosed |
| US-7662846-B2 | Selective spirocyclic glucocorticoid receptor modulators | MERCK SHARP & DOHME CORP. (US) | 2010-02-16 | — | — | US | disclosed |
| US-7662846-B2 | Selective spirocyclic glucocorticoid receptor modulators | MERCK SHARP & DOHME CORP. (US) | 2010-02-16 | — | — | US | disclosed |
| US-7662846-B2 | Selective spirocyclic glucocorticoid receptor modulators | MERCK SHARP & DOHME CORP. (US) | 2010-02-16 | — | — | US | disclosed |
| EP-1617806-B1 | SELECTIVE SPIROCYCLIC GLUCOCORTICOID RECEPTOR MODULATORS | MERCK & CO INC (US) | 2009-11-04 | — | — | EP | disclosed |
| EP-1617806-B1 | SELECTIVE SPIROCYCLIC GLUCOCORTICOID RECEPTOR MODULATORS | MERCK & CO INC (US) | 2009-11-04 | — | — | EP | disclosed |
| EP-1617806-A4 | SELECTIVE SPIROCYCLIC GLUCOCORTICOID RECEPTOR MODULATORS | MERCK & CO INC (US) | 2006-11-02 | — | — | EP | disclosed |
| US-20060217563-A1 | Selective spirocyclic glucocorticoid receptor modulators | MERCK SHARP & DOHME CORP. | 2006-09-28 | — | — | US | disclosed |
| EP-1617806-A2 | SELECTIVE SPIROCYCLIC GLUCOCORTICOID RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2006-01-25 | — | — | EP | disclosed |
| WO-2004093805-A2 | SELECTIVE SPIROCYCLIC GLUCOCORTICOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2004-11-04 | — | — | WO | disclosed |