Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.55 |
| ▸ | KAT2B | Q92831 | 2/20 | 0.48 |
| ▸ | IL1B | P01584 | 3/20 | 0.45 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28934597 | 1.00 | NLRP3 (0.55) | NLRP3KAT2BIL1BEHMT1EHMT2 | |
| SCHEMBL29276148 | 0.90 | NLRP3 (0.56) | NLRP3KAT2BIL1BEHMT1EHMT2 | |
| SCHEMBL29276145 | 0.90 | NLRP3 (0.56) | NLRP3KAT2BIL1BEHMT1EHMT2 | |
| SCHEMBL28963074 | 0.89 | NLRP3 (0.55) | NLRP3KAT2BIL1BEHMT1EHMT2 | |
| SCHEMBL28963072 | 0.89 | NLRP3 (0.55) | NLRP3KAT2BIL1BEHMT1EHMT2 | |
| SCHEMBL28934681 | 0.88 | NLRP3 (0.54) | NLRP3KAT2BIL1BEHMT1EHMT2 | |
| SCHEMBL28934679 | 0.88 | NLRP3 (0.54) | NLRP3KAT2BIL1BEHMT1EHMT2 | |
| SCHEMBL30108792 | 0.87 | NLRP3 (0.66) | NLRP3KAT2BIL1B | |
| SCHEMBL28934690 | 0.87 | NLRP3 (0.66) | NLRP3KAT2BIL1B | |
| SCHEMBL30108860 | 0.87 | NLRP3 (0.66) | NLRP3KAT2BIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |