Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28626542 | 0.86 | SMPD1 (0.42) | MAPTCPB2 | |
| SCHEMBL29284648 | 0.86 | SMPD1 (0.42) | MAPTCPB2 | |
| SCHEMBL234751 | 0.81 | ALDH1A1 (0.46) | POLBALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL3960370 | 0.79 | CHRM1 (0.46) | MAPTCYP3A4CHRM1AKR1A1CHRM3 | |
| SCHEMBL8738949 | 0.79 | ALDH1A1 (0.40) | POLBALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL15443540 | 0.76 | CA1 (0.38) | POLBALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL1227849 | 0.75 | ALDH1A1 (0.40) | POLBALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL14764283 | 0.74 | MGAM (0.38) | POLBALDH1A1LMNAHSD17B10GAA | |
| SCHEMBL13269562 | 0.74 | ALDH1A1 (0.36) | POLBALDH1A1LMNAMAPTHSD17B10 | |
| SCHEMBL13269421 | 0.74 | ALDH1A1 (0.36) | POLBALDH1A1LMNAHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461338-B | 3-azabicyclo (3.1.0) hexane derivatives having KDM5 inhibitory activity and uses thereof | 小野药品工业株式会社 | 2024-02-20 | — | — | CN | disclosed |
| CN-115461338-A | 3-azabicyclo (3.1.0) hexane derivatives having KDM5 inhibitory activity and uses thereof | 小野药品工业株式会社 | 2022-12-09 | — | — | CN | disclosed |