SCHEMBL28935362

SCHEMBL28935362

O=C(Cc1ccc(-c2cccc(OCc3ccc(Cl)cc3F)n2)cc1)Nc1ccc(C(=O)O)cc1NC[C@@H]1CCO1

nearest known ligand 0.49

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 19/20 0.49
PDE10A Q9Y233 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28935367 1.00 GLP1R (0.49) GLP1RPDE10A
SCHEMBL28935449 0.97 GLP1R (0.51) GLP1R
SCHEMBL28935452 0.97 GLP1R (0.51) GLP1R
SCHEMBL28935476 0.97 GLP1R (0.51) GLP1R
SCHEMBL28935400 0.94 GLP1R (0.50) GLP1RPDE10A
SCHEMBL28935398 0.94 GLP1R (0.50) GLP1RPDE10A
SCHEMBL24900099 0.93 GLP1R (0.42) GLP1R
SCHEMBL30139955 0.93 GLP1R (0.42) GLP1R
SCHEMBL28935399 0.93 GLP1R (0.42) GLP1R
SCHEMBL28935482 0.91 GLP1R (0.45) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115279750-B GLP-1 receptor agonist, pharmaceutical composition containing same and preparation method thereof 株式会社LG化学 2024-06-21 CN disclosed
CN-115279750-A GLP-1 receptor agonist, pharmaceutical composition containing same and preparation method thereof 株式会社LG化学 2022-11-01 CN disclosed