SCHEMBL24900099

SCHEMBL24900099

COC(=O)c1ccc(NC(=O)Cc2ccc(-c3cccc(OCc4ccc(Cl)cc4F)n3)cc2)c(NC[C@@H]2CCO2)c1

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30139955 1.00 GLP1R (0.42) GLP1R
SCHEMBL28935399 1.00 GLP1R (0.42) GLP1R
SCHEMBL28935489 0.97 GLP1R (0.44) GLP1R
SCHEMBL30139951 0.97 GLP1R (0.44) GLP1R
SCHEMBL30139945 0.97 GLP1R (0.44) GLP1R
SCHEMBL28935482 0.96 GLP1R (0.45) GLP1R
SCHEMBL30139946 0.94 GLP1R (0.43) GLP1R
SCHEMBL24336904 0.94 GLP1R (0.43) GLP1R
SCHEMBL28935362 0.93 GLP1R (0.49) GLP1R
SCHEMBL28935367 0.93 GLP1R (0.49) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203021-A1 GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME LG CHEM, LTD. (KR) 2023-06-29 US disclosed
EP-4119555-A1 GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME Lg Chem, Ltd. (KR) 2023-01-18 EP disclosed
CN-115279750-A GLP-1 receptor agonist, pharmaceutical composition containing same and preparation method thereof 株式会社LG化学 2022-11-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230203021-A1 GLP-1 RECEPTOR AGONIST, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND METHOD FOR PREPARING SAME GLP1R, GIPR, GPR119 GLP1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.