Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | GOT1 | P17174 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16249702 | 0.81 | MAP4K4 (0.55) | JAK3ALDH1A1MAP4K4 | |
| SCHEMBL22576043 | 0.76 | TP53 (0.45) | JAK3KDM4EALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL29727823 | 0.75 | HRH3 (0.41) | JAK3KDM4EALDH1A1SMN1; SMN2CYP3A4 | |
| SCHEMBL29931500 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2HCAR2CYP3A4 | |
| SCHEMBL5239212 | 0.75 | KDM4E (0.68) | KDM4EALDH1A1SMN1; SMN2HCAR2CYP3A4 | |
| SCHEMBL27881017 | 0.73 | MAP4K4 (0.41) | JAK3KDM4EALDH1A1SMN1; SMN2HCAR2 | |
| SCHEMBL3721191 | 0.72 | MAPK14 (0.46) | KDM4EALDH1A1MGLLCYP3A4GHSR | |
| SCHEMBL27952422 | 0.71 | HCAR2 (0.47) | KDM4EALDH1A1SMN1; SMN2HCAR2CYP3A4 | |
| SCHEMBL1225685 | 0.71 | ALDH1A1 (0.51) | KDM4EALDH1A1SMN1; SMN2HCAR2CYP3A4 | |
| SCHEMBL12723984 | 0.70 | HCAR2 (0.55) | KDM4EALDH1A1SMN1; SMN2HCAR2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279770-A | Compounds and compositions for treating diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2022-11-01 | — | — | CN | disclosed |