⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995359 | 0.77 | NOTUM (0.40) | — | |
| SCHEMBL7991853 | 0.74 | — | — | |
| SCHEMBL5004908 | 0.73 | NOTUM (0.44) | — | |
| SCHEMBL21572924 | 0.73 | — | — | |
| SCHEMBL28860067 | 0.73 | — | — | |
| SCHEMBL27487992 | 0.73 | — | — | |
| SCHEMBL4379296 | 0.71 | POLB (0.43) | — | |
| SCHEMBL21407447 | 0.71 | NOTUM (0.42) | — | |
| SCHEMBL8102800 | 0.70 | NOTUM (0.41) | — | |
| SCHEMBL21407436 | 0.70 | TRIM24 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115279770-A | Compounds and compositions for treating diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2022-11-01 | — | — | CN | disclosed |