Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 4/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5004908 | 0.84 | NOTUM (0.44) | POLBAPEX1TDP1L3MBTL1NOTUM | |
| SCHEMBL14398922 | 0.83 | POLB (0.41) | POLBAPEX1TDP1L3MBTL1NOTUM | |
| SCHEMBL4334753 | 0.82 | TDP1 (0.46) | POLBAPEX1TDP1L3MBTL1HDAC4 | |
| SCHEMBL30034979 | 0.81 | NOTUM (0.41) | POLBAPEX1TDP1L3MBTL1NOTUM | |
| SCHEMBL4904690 | 0.78 | TDP1 (0.43) | POLBAPEX1TDP1L3MBTL1HDAC4 | |
| SCHEMBL4905375 | 0.78 | POLB (0.40) | POLBAPEX1TDP1L3MBTL1HDAC4 | |
| SCHEMBL4913277 | 0.78 | POLB (0.40) | POLBAPEX1TDP1L3MBTL1HDAC4 | |
| SCHEMBL19500072 | 0.78 | KDM4E (0.41) | POLBTDP1L3MBTL1NOTUMALDH1A1 | |
| SCHEMBL26119733 | 0.75 | LPO (0.45) | POLBAPEX1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL6794236 | 0.74 | L3MBTL1 (0.40) | POLBAPEX1TDP1L3MBTL1HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563094-B | (hetero) aryl-substituted piperidinyl derivatives, process for their preparation and pharmaceutical compositions containing them | 法国施维雅药厂 | 2022-03-18 | — | — | CN | disclosed |
| WO-2009125191-A1 | BENZENE DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2009-10-15 | — | — | WO | disclosed |