Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 18/20 | 0.40 |
| ▸ | CSF1R | P07333 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28935794 | 0.99 | MAP4K1 (0.40) | MAP4K1CSF1RCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28935696 | 0.81 | TTK (0.33) | — | |
| SCHEMBL29878025 | 0.79 | MAP4K1 (0.46) | MAP4K1 | |
| SCHEMBL29878464 | 0.79 | MAP4K1 (0.42) | MAP4K1 | |
| SCHEMBL28935921 | 0.79 | MAP4K1 (0.49) | MAP4K1 | |
| Hydrochloric Acid SCHEMBL31484039 | 0.78 | WEE1 (0.35) | — | |
| SCHEMBL29878261 | 0.77 | MAP4K1 (0.45) | MAP4K1 | |
| SCHEMBL23104087 | 0.75 | MAP4K1 (0.67) | MAP4K1 | |
| SCHEMBL30324528 | 0.75 | MAP4K1 (0.67) | MAP4K1 | |
| SCHEMBL23103616 | 0.73 | MAP4K1 (0.62) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611925-A | HPK1 inhibitors and uses thereof | 轩竹生物科技股份有限公司 | 2023-01-17 | — | — | CN | disclosed |