Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29878025 | 0.87 | MAP4K1 (0.46) | MAP4K1 | |
| SCHEMBL29878261 | 0.82 | MAP4K1 (0.45) | MAP4K1 | |
| SCHEMBL29878089 | 0.81 | TTK (0.36) | — | |
| SCHEMBL28935921 | 0.81 | MAP4K1 (0.49) | MAP4K1 | |
| SCHEMBL28935698 | 0.79 | MAP4K1 (0.40) | MAP4K1 | |
| Hydrochloric Acid SCHEMBL28935794 | 0.78 | MAP4K1 (0.40) | MAP4K1 | |
| SCHEMBL23104087 | 0.77 | MAP4K1 (0.67) | MAP4K1 | |
| SCHEMBL30324528 | 0.77 | MAP4K1 (0.67) | MAP4K1 | |
| SCHEMBL23103616 | 0.76 | MAP4K1 (0.62) | MAP4K1 | |
| SCHEMBL30323835 | 0.76 | MAP4K1 (0.62) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114940683-B | HPK1 inhibitors and uses thereof | 轩竹(北京)医药科技有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-114940683-A | HPK1 inhibitors and uses thereof | 轩竹(北京)医药科技有限公司 | 2022-08-26 | — | — | CN | disclosed |