Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5300656 | 0.82 | TP53 (0.46) | TP53TAAR1SLC6A2SLC6A4MAOA | |
| Bromide SCHEMBL2178786 | 0.73 | TP53 (0.36) | TP53L3MBTL1 | |
| Ethylbenzene SCHEMBL11263486 | 0.71 | TP53 (0.74) | TP53TAAR1SLC6A2SLC6A4MAOA | |
| SCHEMBL14990350 | 0.70 | TP53 (0.38) | TP53 | |
| SCHEMBL5293853 | 0.70 | TP53 (0.47) | TP53SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL31547020 | 0.70 | — | — | |
| SCHEMBL15583887 | 0.69 | ALDH1A1 (0.38) | TP53ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL3206603 | 0.69 | — | — | |
| SCHEMBL30069404 | 0.69 | — | — | |
| Bromide SCHEMBL28403647 | 0.68 | TP53 (0.43) | TP53TAAR1CYP2D6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115465902-A | Reaction solvent for preparing superfine nickel oxide nanoparticles and method for preparing superfine nickel oxide by using reaction solvent | 河北科技大学 | 2022-12-13 | — | — | CN | claimed |