Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.56 |
| ▸ | RELA | Q04206 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29669758 | 1.00 | MAPT (0.64) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6295069 | 0.85 | KMT2A (0.58) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL27942800 | 0.83 | KMT2A (0.72) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL3604124 | 0.80 | KMT2A (0.74) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1454119 | 0.79 | KMT2A (0.73) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1455196 | 0.79 | KMT2A (0.73) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1455800 | 0.79 | KMT2A (0.73) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL15176813 | 0.78 | MEN1 (0.68) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL1455286 | 0.78 | KMT2A (0.90) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7296050 | 0.78 | RAB9A (0.69) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108863892-B | Gallic acid methyl ester analogue containing amide structure and application thereof | 温州医科大学 | 2022-04-05 | — | — | CN | disclosed |