Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | GRM5 | P41594 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937139 | 0.87 | RXFP1 (0.71) | F2RXFP1KMT2AMEN1MAPT | |
| SCHEMBL28937132 | 0.87 | KMT2A (0.70) | F2RXFP1KMT2AMEN1CYP1A2 | |
| SCHEMBL28937134 | 0.86 | MAPT (0.64) | F2RXFP1KMT2AMEN1MAPT | |
| SCHEMBL28937142 | 0.84 | MEN1 (0.60) | RXFP1KMT2AMEN1CCNA2CDK2 | |
| SCHEMBL28542399 | 0.79 | KDM4E (0.70) | RXFP1KMT2AMEN1GAAMAPT | |
| SCHEMBL20177032 | 0.78 | RXFP1 (0.57) | RXFP1KMT2AMEN1CCNA2CDK2 | |
| SCHEMBL16899070 | 0.77 | SMN1; SMN2 (0.64) | RXFP1KMT2AMEN1MAPTCCNA2 | |
| SCHEMBL18247131 | 0.75 | GRM5 (0.51) | GAAMAPTCYP1A2POLBRECQL | |
| SCHEMBL29597769 | 0.75 | GRM5 (0.51) | GAAMAPTCYP1A2POLBRECQL | |
| SCHEMBL19150932 | 0.75 | GRM5 (0.52) | RXFP1GAAMAPTCYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272425-B | Pyridyloxyl octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |