Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 4/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937146 | 0.87 | KMT2A (0.79) | MEN1KMT2AKDM4ELMNARXFP1 | |
| SCHEMBL28937135 | 0.86 | RXFP1 (0.78) | MEN1KMT2AKDM4ELMNARXFP1 | |
| SCHEMBL28937159 | 0.84 | MEN1 (0.60) | MEN1KMT2AKDM4ELMNARXFP1 | |
| SCHEMBL28937136 | 0.84 | F2 (0.53) | MEN1KMT2ARXFP1TP53GRM5 | |
| SCHEMBL20177032 | 0.81 | RXFP1 (0.57) | MEN1KMT2ALMNARXFP1TP53 | |
| SCHEMBL16899070 | 0.78 | SMN1; SMN2 (0.64) | MEN1KMT2ALMNARXFP1TP53 | |
| SCHEMBL821839 | 0.76 | KMT2A (1.00) | MEN1KMT2ARXFP1GRM5CCNA2 | |
| SCHEMBL23286796 | 0.76 | KMT2A (0.77) | MEN1KMT2ARXFP1GRM5CCNA2 | |
| SCHEMBL29738098 | 0.76 | KMT2A (0.77) | MEN1KMT2ARXFP1GRM5CCNA2 | |
| SCHEMBL2251120 | 0.75 | KDM4E (1.00) | MEN1KMT2AKDM4ELMNAGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272425-B | Pyridyloxyl octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |