Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MGAM | O43451 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | SI | P14410 | 3/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MPO | P05164 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937263 | 1.00 | MEN1 (0.42) | MEN1KMT2AMAPTMGAMGAA | |
| SCHEMBL31642219 | 0.78 | KMT2A (0.53) | MEN1KMT2AMAPTMGAMGAA | |
| SCHEMBL31642547 | 0.78 | KMT2A (0.53) | MEN1KMT2AMAPTMGAMGAA | |
| SCHEMBL31646013 | 0.78 | KMT2A (0.53) | MEN1KMT2AMAPTMGAMGAA | |
| SCHEMBL31642403 | 0.78 | KMT2A (0.53) | MEN1KMT2AMAPTMGAMGAA | |
| SCHEMBL31642357 | 0.78 | KMT2A (0.53) | MEN1KMT2AMAPTMGAMGAA | |
| SCHEMBL29199765 | 0.73 | KDM4E (0.58) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL29199770 | 0.73 | KDM4E (0.58) | MEN1KMT2AMAPTKDM4ETSHR | |
| SCHEMBL9056837 | 0.73 | CYP2D6 (0.61) | MEN1KMT2AMAPTMGAMGAA | |
| SCHEMBL10372734 | 0.73 | GPR84 (0.47) | MEN1KMT2AMAPTMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299420-B | Pentacyclic compounds as selective estrogen receptor down-regulators and uses thereof | 南京圣和药业股份有限公司 | 2021-10-15 | — | — | CN | disclosed |