Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 0.58 |
| ▸ | SNCA | P37840 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA3 | P07451 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA5A | P35218 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29493348 | 1.00 | KDM4E (0.59) | KDM4EMAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL584262 | 0.89 | KDM4E (0.73) | KDM4EMAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL584263 | 0.89 | KDM4E (0.73) | KDM4EMAPK1ALDH1A1HPGDALOX15 | |
| Hydrochloric Acid SCHEMBL6818633 | 0.88 | KDM4E (0.71) | KDM4EMAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL6782737 | 0.86 | KDM4E (0.79) | KDM4EMAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL7821694 | 0.86 | KDM4E (0.79) | KDM4EMAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL23805173 | 0.81 | KDM4E (0.80) | KDM4EMAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL9329936 | 0.81 | KDM4E (0.80) | KDM4EMAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL4651235 | 0.81 | KDM4E (0.80) | KDM4EMAPK1ALDH1A1HPGDALOX15 | |
| SCHEMBL29090925 | 0.80 | TUBB1 (0.66) | KDM4EMAPK1ALDH1A1HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149386-A | Aryl pentadiene amide aldehyde dehydrogenase inhibitor, and synthesis method and application thereof | 中国人民解放军第二军医大学 | 2022-03-08 | — | — | CN | disclosed |