Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937879 | 0.81 | BRD4 (0.45) | MAOBMAOAALDH1A1BRD4ERN1 | |
| SCHEMBL28937854 | 0.81 | BRD4 (0.42) | MAOBMAOAMEN1KMT2ABRD4 | |
| SCHEMBL28937852 | 0.80 | MAPT (0.43) | MAOBGAAMAOAKDM4EALDH1A1 | |
| SCHEMBL11550337 | 0.80 | BRD4 (0.59) | KDM4EALDH1A1BRD4ERN1HSD17B10 | |
| SCHEMBL11391596 | 0.74 | GAA (0.50) | MAOBGAAMAOAKDM4EALDH1A1 | |
| SCHEMBL11431671 | 0.73 | EGFR (0.50) | MAOBGAAMAOAKDM4EALDH1A1 | |
| SCHEMBL28937848 | 0.72 | SMN1; SMN2 (0.47) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL21052803 | 0.72 | BRD4 (0.39) | GAAKDM4EALDH1A1BRD4ERN1 | |
| SCHEMBL11610416 | 0.72 | GAA (0.55) | GAAKDM4EALDH1A1EGFRMEN1 | |
| SCHEMBL28937872 | 0.72 | ADORA1 (0.45) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611816-A | Method for efficiently preparing 5-aryl (hetero) ring modified uracil derivative | 中国科学院化学研究所 | 2023-01-17 | — | — | CN | disclosed |