Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937876 | 0.83 | BRD4 (0.44) | BRD4LMNAKDM4EALDH1A1ERN1 | |
| SCHEMBL28937905 | 0.81 | KMT2A (0.47) | BRD4ERN1HSD17B10 | |
| SCHEMBL28937852 | 0.81 | MAPT (0.43) | BRD4LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28937862 | 0.80 | MAOB (0.50) | BRD4KDM4EALDH1A1ERN1ADORA2A | |
| SCHEMBL21052803 | 0.80 | BRD4 (0.39) | BRD4LMNAKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL28937879 | 0.80 | BRD4 (0.45) | BRD4ALDH1A1ERN1HSD17B10 | |
| SCHEMBL28937854 | 0.80 | BRD4 (0.42) | BRD4MAPK1ERN1 | |
| SCHEMBL28937901 | 0.79 | ERN1 (0.49) | BRD4KDM4EALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL28963435 | 0.78 | TDP2 (0.43) | ERN1ADORA2ABRD9 | |
| SCHEMBL28937874 | 0.77 | MAPT (0.47) | BRD4LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611816-A | Method for efficiently preparing 5-aryl (hetero) ring modified uracil derivative | 中国科学院化学研究所 | 2023-01-17 | — | — | CN | disclosed |
| CN-106349170-A | Preparation method of 1,3-dimethyl-5-phenyluracil | 东华大学 | 2017-01-25 | — | — | CN | disclosed |
| CN-106349170-A | Preparation method of 1,3-dimethyl-5-phenyluracil | 东华大学 | 2017-01-25 | — | — | CN | disclosed |
| US-4171429-A | Pyrimidine to pyrimidine transformation process | RESEARCH CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |